Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC732H1155N215O217S7

DescriptionStandard

        MAKVQFTKRQETSQIFVHCSATKATMDVGVREIRQWHKEQGWLDVGYHFIIRRDGTVEAGRDQDAVGSHVKGYNSTSVGVCLVGGIDAKGNPEANFTPQQMSALKGLLHELKGTYPKAVIMAHHDVAPKACPSFDLQRWVKTGELVTSDRG
    

Molecular Weight16663.77 Da

Isoelectric Point (pI)8.81

Net Charge (pH 7.0)3.10

Net Charge (pH 7.4) 2.44

Charge Density (pH 7.0) 0.0205

GRAVY Index-0.41

Hydrophobic Moment 0.75

Boman Index-0.03

Instability Index38.38

Aliphatic Index 72.91

Aromaticity 0.0728

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6952.63

LogP -73.75

H-bond Donors 244.0

H-bond Acceptors 234.0

Rotatable Bonds 556.0

Heavy Atoms 1171.0

Ring Count 26.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0284297 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage 2044-307w [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic

RECORD: Rec_0301952 VERIFIED: NO