Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length154 amino acids

Chemical FormulaC765H1228N206O229S7

DescriptionStandard

        MQLSRKGLEAIKFFEGLKLEAYEDSAGIPTIGYGTIRIDGKPVKMGMKITAEQAEQYLLADIEKFVAAVNKSIKVPTSQNEFDALVSETYNIGITAMQDSTFIKRHNAGDKVGCAEAMQWWNKVTVKGKKVTSNGLKNRRRMEADIYLDSVYPK
    

Molecular Weight17199.63 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)3.59

Net Charge (pH 7.4) 3.26

Charge Density (pH 7.0) 0.0233

GRAVY Index-0.38

Hydrophobic Moment 0.69

Boman Index-0.02

Instability Index32.09

Aliphatic Index 81.10

Aromaticity 0.0844

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 19940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7088.62

LogP -67.08

H-bond Donors 245.0

H-bond Acceptors 241.0

Rotatable Bonds 592.0

Heavy Atoms 1207.0

Ring Count 20.0

Amide Bonds 166.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0042488 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage mio [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic