Peptide Database

Peptide NameEppin (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1)

Function Ontology

Antimicrobial

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length133 amino acids

Chemical FormulaC663H1035N193O191S16

DescriptionStandard

        MGSSGLLSLLVLFILLVNVQGPGLTDWLFPRRCPTIREECEFRERDVCTRHRQCPDNKKCCVFSCGKKCLDLKQDVCEMPNETGPCLAFFIRWWYDKKNNTCSTFVHGGCQGNNNNFQSEANCLNTCKNKRFP
    

Molecular Weight15278.53 Da

Isoelectric Point (pI)8.55

Net Charge (pH 7.0)4.55

Net Charge (pH 7.4) 4.00

Charge Density (pH 7.0) 0.0342

GRAVY Index-0.42

Hydrophobic Moment 0.49

Boman Index-0.09

Instability Index56.99

Aliphatic Index 63.68

Aromaticity 0.0977

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 18865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6239.65

LogP -66.37

H-bond Donors 226.0

H-bond Acceptors 214.0

Rotatable Bonds 504.0

Heavy Atoms 1063.0

Ring Count 25.0

Amide Bonds 149.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0330115 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

Tax ID9544

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Protease inhibitor Serine protease inhibitor Enzyme inhibitory Non-hemolytic