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MYP_144270
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Basic Information
61(derived from FIV envelope glycoprotein )
Antimicrobial
Antiviral
Antiviral ▸ Anti-Retrovirus ▸ Anti-Lentivirus ▸ Anti-FIV
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Standard
20 amino acids
C95H170N20O21S
Standard
Sequence
LLGGILGIGLGVLLLILCLP
Physicochemical Analysis
1960.55 Da
5.52
-0.25
-0.47
-0.0125
2.54
0.17
0.88
45.70
248.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
607.43
1.41
21.0
22.0
64.0
137.0
1.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017023 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Feline immunodeficiency virus (FIV):inhibition of virus replication in Crandell feline kidney
88 %
Inhibition
PaperPubMed PMID: 8661378 PMID8661378 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8661378/
RECORD: Rec_0228176 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 8661378 PMID8661378 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8661378/
RECORD: Rec_0260011 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-FIV Replication inhibition
Feline immunodeficiency virus (FIV) | fibroblastoid cells
16 μg/mL
% inhibition
Mammalian: 5.5 h; Yeast: 3 min; E. coli: 2 min
PaperInhibition of feline immunodeficiency virus infection in vitro by envelope glycoprotein synthetic peptides. | Lombardi S, Massi C, Indino E, La Rosa C, Mazzetti P, Falcone ML, Rovero P, Fissi A, Pieroni O, Bandecchi P, Esposito F, Tozzini F, Bendinelli M, Garzelli C. | Virology. 1996 Jun 15;220(2):274-84. | DOI:10.1006/viro.1996.0315 | PMID:8661378 PMID8661378 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8661378/
RECORD: Rec_0394423 VERIFIED: YES
Provenance & Taxonomy
Feline immunodeficiency virus [Virus]
Virus-derived peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Fusion inhibitor
Feline immunodeficiency virus (Syncytium formation); CrFK
88 %
Syncytia assay
PaperInhibition of feline immunodeficiency virus infection in vitro by envelope glycoprotein synthetic peptides. | Lombardi S, Massi C, Indino E, La Rosa C, Mazzetti P, Falcone ML, Rovero P, Fissi A, Pieroni O, Bandecchi P, Esposito F, Tozzini F, Bendinelli M, Garzelli C. | Virology. 1996 | PMID:8661378 PMID8661378 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8661378/
RECORD: Rec_0427349 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/