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MYP_144261
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Basic Information
Phakellistatin 22
Anticancer
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
10 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
PPXFELPPYI
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0052901 VERIFIED: YES
Provenance & Taxonomy
Stylissa flabelliformis [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Methionine sulfone
Bio-Activity Profile
Antimicrobial Anticancer
K562
0.021 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0061228 VERIFIED: YES
Provenance & Taxonomy
Phakellia fusca [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Methionine sulfone
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: SNU-638
0.01 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0088634 VERIFIED: YES
Provenance & Taxonomy
Stylissa flabelliformis [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Methionine sulfone
Bio-Activity Profile
Antimicrobial Anticancer
HCT 116
0.14 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0140096 VERIFIED: YES
Provenance & Taxonomy
Stylissa flabelliformis [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Methionine sulfone
Bio-Activity Profile
Antimicrobial Anticancer
SNU-638
0.16 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0140528 VERIFIED: YES
Provenance & Taxonomy
Phakellia fusca [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Methionine sulfone
Bio-Activity Profile
Antimicrobial Anticancer
A549
0.19 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
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