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MYP_144212
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Basic Information
RN3(5-17P22-36)[Q12I]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
30 amino acids
C172H265N55O38S
Standard
Sequence
RPFTRAQWFAIIHISPRTIAMRAINNYRWR
Physicochemical Analysis
3743.35 Da
12.00
5.85
5.59
0.1949
-0.40
0.48
-0.12
64.34
78.33
0.1667
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1531.49
-11.27
57.0
46.0
116.0
266.0
10.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0095545 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human hepatocellular carcinoma HepG2
59.64
IC50
PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
RECORD: Rec_0159008 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
MRC-5
100 μM
IC50
PaperPubMed PMID: 29763807 PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
RECORD: Rec_0301465 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
Human fibroblasts MRC-5
>100 μM
IC50
PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
RECORD: Rec_0354026 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Hep-G2
59.64±6.17 μM
IC50
PaperPubMed PMID: 29763807 PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
RECORD: Rec_0365883 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa PAO1
0.44
ED50
PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
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