Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length181 amino acids

Chemical FormulaC884H1411N259O242S13

DescriptionStandard

        IRSLLSQGFFHSLRWGTCLVSDLRHCLRKFCPSFRAQQAPEGVADQFPRSWLRSQAAWGPHGLILPLRSAARSTAVICSAIKAGLEAARLSISARSSCVLSSSLPRSSEAMTQLLLLLVALLVLGHAPPGRSEFKRCWKGQGACRTYCTRQETYMHLCPDASLCCLSYALKPPPVPRPEYE
    

Molecular Weight19956.10 Da

Isoelectric Point (pI)9.55

Net Charge (pH 7.0)12.11

Net Charge (pH 7.4) 11.46

Charge Density (pH 7.0) 0.0669

GRAVY Index0.01

Hydrophobic Moment 0.75

Boman Index0.03

Instability Index79.14

Aliphatic Index 88.51

Aromaticity 0.0773

Extinction Coeff. Reduced 27960.00

Extinction Coeff. Oxidized 28585.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7932.30

LogP -90.57

H-bond Donors 294.0

H-bond Acceptors 272.0

Rotatable Bonds 638.0

Heavy Atoms 1398.0

Ring Count 37.0

Amide Bonds 188.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0260645 VERIFIED: NO

Provenance & Taxonomy

OrganismCallithrix jacchus [Animal]

FamilyDefensin

Tax ID9483

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal