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MYP_144180
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Basic Information
Ceratotoxin D
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
36 amino acids
C163H293N43O41
Standard
Sequence
SIGTAVKKAVPIAKKVGKVAIPIAKAVLSVVGQLVG
Physicochemical Analysis
3511.33 Da
10.70
5.45
5.24
0.1515
1.00
0.63
0.33
-3.04
146.11
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1324.14
-10.05
45.0
47.0
119.0
247.0
2.0
36.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0324497 VERIFIED: YES
Provenance & Taxonomy
Ceratitis capitata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0335667 VERIFIED: YES
Provenance & Taxonomy
Ceratitis capitata [Animal]
Ceratotoxin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic Anti-mammalian cells
PaperInsect Biochem. Mol. Biol. 1997; 27:1039-1046 | http://www.sciencedirect.com/science/article/pii/S0965174897000908
RECORD: Rec_0351338 VERIFIED: YES
Provenance & Taxonomy
Ceratitis capitata [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PaperPubMed PMID: 9569644 PMID9569644 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9569644/
RECORD: Rec_0401244 VERIFIED: YES
Provenance & Taxonomy
Ceratitis capitata [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-positive and Gram-negative bacteria
PaperPubMed PMID: 9569644 PMID9569644 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9569644/
RECORD: Rec_0415270 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 94.4%, E 0.0%, T 0.0%, C 5.6% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
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