Peptide Database

Peptide NameNeuropeptide AF-like

Function Ontology

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC65H91N17O15

DescriptionStandard

        QFWSLAAPQRF
    

Molecular Weight1350.52 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0691

GRAVY Index-0.16

Hydrophobic Moment 0.09

Boman Index0.11

Instability Index37.25

Aliphatic Index 53.64

Aromaticity 0.2727

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 529.63

LogP -3.17

H-bond Donors 18.0

H-bond Acceptors 16.0

Rotatable Bonds 39.0

Heavy Atoms 97.0

Ring Count 5.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004156 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyFMRFamide related peptide

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0112977 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyNeuropeptide AF-like

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Receptor modulation

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0176694 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyNeuropeptide AF-like

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Receptor modulation

TargetM2 macrophage-associated genes IL-4 receptor

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0317385 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication