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MYP_144156
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Basic Information
Neuromedin U-25
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
25 amino acids
C140H216N44O37
Standard
Sequence
FRLDEEFQGPIASQVRRQFLFRPRN
Physicochemical Analysis
3107.49 Da
11.40
1.77
1.56
0.0707
-0.88
0.52
-0.31
64.55
62.40
0.1600
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1358.13
-12.35
47.0
39.0
102.0
221.0
6.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007943 VERIFIED: NO
Provenance & Taxonomy
Canis familiaris [Animal]
9615
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0116644 VERIFIED: YES
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Neuromedin-U
9615
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
18:Pyrrolidone carboxylic acid
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Myotropic
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Neuromedin-U-25 (Canis lupus familiaris): PMID 2052487 PMID2052487 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2052487/
RECORD: Rec_0170139 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0345004 VERIFIED: NO
Provenance & Taxonomy
Canis familiaris [Animal]
Neuromedins
9615
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Hormone