Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC359H570N98O97S9

DescriptionStandard

        MTQLLLLIVALLVLGHVPPGRTEFKRCWKGQGTCRTYCTKQESFIHLCPDASLCCLSYMFRPSRPPMPDNE
    

Molecular Weight8099.55 Da

Isoelectric Point (pI)8.64

Net Charge (pH 7.0)2.63

Net Charge (pH 7.4) 2.20

Charge Density (pH 7.0) 0.0370

GRAVY Index-0.04

Hydrophobic Moment 0.54

Boman Index0.04

Instability Index62.02

Aliphatic Index 80.99

Aromaticity 0.0845

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3080.89

LogP -26.12

H-bond Donors 112.0

H-bond Acceptors 111.0

Rotatable Bonds 257.0

Heavy Atoms 563.0

Ring Count 16.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0274201 VERIFIED: NO

Provenance & Taxonomy

OrganismFukomys damarensis [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic