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MYP_144132
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Basic Information
AMP 1A analogs6
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
20 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GFXGXKXGXFXGXGKXKKKK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0238905 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
contains non-canonical/unspecified residues (X); stereochemistry not fully specified [Other]
unspecified non-canonical residue at 3,5,7,9,11,13,16
Bio-Activity Profile
Antimicrobial Antibacterial
Human pancreatic carcinoma Mia PaCa-2
7.5 μM
IC50
PMID27387357 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27387357/
RECORD: Rec_0252850 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
contains non-canonical/unspecified residues (X); stereochemistry not fully specified [Other]
unspecified non-canonical residue at 3,5,7,9,11,13,16
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
42 μM
MIC
PMID27387357 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27387357/
RECORD: Rec_0259929 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
contains non-canonical/unspecified residues (X); stereochemistry not fully specified [Other]
unspecified non-canonical residue at 3,5,7,9,11,13,16
Bio-Activity Profile
Antimicrobial Antibacterial
Burkholderia pseudomallei NCTC 8016
46 μM
MIC
PMID27387357 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27387357/
RECORD: Rec_0265395 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
contains non-canonical/unspecified residues (X); stereochemistry not fully specified [Other]
unspecified non-canonical residue at 3,5,7,9,11,13,16
Bio-Activity Profile
Antimicrobial Antibacterial
Human lung carcinoma NCI-H69
7.5 μM
IC50
PMID27387357 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27387357/
RECORD: Rec_0268201 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic designed peptide
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Acetylation
Amidation
A6c = 1-aminocyclohexane carboxylic acid, Oic = Octahydroindolecarboxylic acid
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis MDR
20.92 μM
MIC
PMID27387357 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27387357/
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