Peptide Database

Peptide NameAstexin-1 (Class II lasso peptide) (Ribosomally synthesized and post-translationally modified peptide) (RiPP)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC239H388N66O81S

DescriptionStandard

        MHTPIISETVQPKTAGLIVLGKASAETRGLSQGVEPDIGQTYFEESRINQD
    

Molecular Weight5514.10 Da

Isoelectric Point (pI)4.84

Net Charge (pH 7.0)-3.40

Net Charge (pH 7.4) -3.68

Charge Density (pH 7.0) -0.0666

GRAVY Index-0.40

Hydrophobic Moment 0.48

Boman Index0.02

Instability Index44.43

Aliphatic Index 84.12

Aromaticity 0.0392

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2375.32

LogP -27.51

H-bond Donors 80.0

H-bond Acceptors 80.0

Rotatable Bonds 184.0

Heavy Atoms 387.0

Ring Count 6.0

Amide Bonds 55.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0145828 VERIFIED: YES

Provenance & Taxonomy

OrganismAsticcacaulis excentricus [Bacterium]

Tax ID573065

Structure & Mods

Configlasso-peptide topology [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic

TargetNo Target Organism Found