Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length472 amino acids

Chemical FormulaC2383H3714N596O694S16

DescriptionStandard

        MRYICTGVQAGIEMIEQMAKERNIPDLKGSESLEFLKIDYVNYNFTNIKIHALSFPNTSLAFVPGVGIKALTNHGMANISTNWEVKSPLFQDTGGADLFLSGVYFTGLLILTRNDFGHPTLQLQDCYSQVSHAHVSFSGELSVLYNSFAEPMEKPILKNLNEMLCPIITGEVEALNANLSMLEVLTKMDNYTLLDFSLLNAPEITENNIDLDLKGVFYPLENLADPPFPSVPFVLPERSDSMLYIGISEYFFKSASFAYFTAGAFNVTLSTKEISSHLVQNSQGVGNVLSRIAEIYILSQPFMIRIMATAPPVINLLPGNFTLDIPASIVILTQPENSTVETIVSMDFVASTSVGLVILGQRLICSLSLNRFRLTLPKSSRSNIEVLRFENILSFIIHFGILPLANAKLQQGFPLPNPHKISFVNSDIEVLEHFLLISTDLRYETSLKQQPSFHGWEGLNLISGQWSGNSAP
    

Molecular Weight52329.60 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-15.60

Net Charge (pH 7.4) -16.48

Charge Density (pH 7.0) -0.0331

GRAVY Index0.18

Hydrophobic Moment 0.64

Boman Index0.19

Instability Index40.95

Aliphatic Index 105.13

Aromaticity 0.0975

Extinction Coeff. Reduced 35870.00

Extinction Coeff. Oxidized 36120.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0072165 VERIFIED: NO

Provenance & Taxonomy

OrganismRousettus aegyptiacus (Egyptian rousette) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria