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MYP_144108
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Basic Information
Rugosin-LK1
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
75 amino acids
C369H607N93O119S7
Standard
Sequence
MFTMKKSLLFLFFLGTISLSFCEEERSADEDDEGEMTEEEKRSIRDKIKTMAIDLAKSAGTGVLKTLICKLDKSC
Physicochemical Analysis
8474.77 Da
4.92
-3.51
-3.80
-0.0468
-0.20
0.67
-0.05
41.74
82.00
0.0667
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3459.09
-31.99
125.0
123.0
303.0
588.0
5.0
74.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004703 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Staphylococcus aureus (Gram-positive)
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
RECORD: Rec_0102791 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Escherichia coli (Gram-negative)
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
RECORD: Rec_0106177 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Pseudomonas aeruginosa (Gram-negative)
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
RECORD: Rec_0175543 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Candida albicans
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
RECORD: Rec_0189696 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Bacillus subtilis (Gram-positive)
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
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