Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC349H557N105O84S8

DescriptionStandard

        MKIHLFFFILLFGVTILPARKRFPHYGSVDMRRQCVKGNGRCKNECHVSEVRIAYCLRPGTHCCLQK
    

Molecular Weight7824.33 Da

Isoelectric Point (pI)9.81

Net Charge (pH 7.0)8.79

Net Charge (pH 7.4) 8.27

Charge Density (pH 7.0) 0.1312

GRAVY Index-0.04

Hydrophobic Moment 0.49

Boman Index-0.03

Instability Index63.68

Aliphatic Index 82.84

Aromaticity 0.1045

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3041.31

LogP -24.37

H-bond Donors 114.0

H-bond Acceptors 105.0

Rotatable Bonds 259.0

Heavy Atoms 546.0

Ring Count 14.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0122812 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyDefensin

Tax ID9940

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence