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MYP_144097
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Basic Information
Ohmyungsamycin B
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
12 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
VXVXXVXVXTVX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0328724 VERIFIED: YES
Provenance & Taxonomy
Streptomyces sp. [Bacterium]
Structure & Mods
linear peptide [Linear]
contains non-canonical/unspecified residues (X); stereochemistry not fully specified [Other]
unspecified non-canonical residue at 2,4,5,7,9,12
Bio-Activity Profile
Cytotoxic
Normal human lung fibroblast MRC-5 cells
>40 μM
Cytotoxicity IC50 assay
PMID24266328 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24266328/
RECORD: Rec_0331891 VERIFIED: NO
Provenance & Taxonomy
Streptomyces sp. [Bacterium]
Structure & Mods
linear peptide [Linear]
contains non-canonical/unspecified residues (X); stereochemistry not fully specified [Other]
unspecified non-canonical residue at 2,4,5,7,9,12
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 6538P
PMID24266328 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24266328/
RECORD: Rec_0332576 VERIFIED: YES
Provenance & Taxonomy
Streptomyces sp. [Bacterium]
Structure & Mods
linear peptide [Linear]
contains non-canonical/unspecified residues (X); stereochemistry not fully specified [Other]
unspecified non-canonical residue at 2,4,5,7,9,12
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis ATCC 6633
4.28 μM
MIC
PMID24266328 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24266328/
RECORD: Rec_0365392 VERIFIED: YES
Provenance & Taxonomy
Streptomyces sp. [Bacterium]
Structure & Mods
linear peptide [Linear]
contains non-canonical/unspecified residues (X); stereochemistry not fully specified [Other]
unspecified non-canonical residue at 2,4,5,7,9,12
Bio-Activity Profile
Antimicrobial Antibacterial
Proteus hauseri NBRC 3851
2.14 μM
MIC
PMID24266328 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24266328/
RECORD: Rec_0404618 VERIFIED: YES
Provenance & Taxonomy
Streptomyces sp. [Bacterium]
Structure & Mods
linear peptide [Linear]
contains non-canonical/unspecified residues (X); stereochemistry not fully specified [Other]
unspecified non-canonical residue at 2,4,5,7,9,12
Bio-Activity Profile
Antimicrobial Antibacterial
Proteus hauseri NBRC 3851
17 μM
MIC
PMID24266328 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24266328/
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