Peptide Database

Peptide NamePG 97-269

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC148H243N43O38

DescriptionStandard

        HFDAVFTNSYRKVLKRLSARKLLQDIL
    

Molecular Weight3232.78 Da

Isoelectric Point (pI)10.43

Net Charge (pH 7.0)3.85

Net Charge (pH 7.4) 3.58

Charge Density (pH 7.0) 0.1424

GRAVY Index-0.18

Hydrophobic Moment 0.71

Boman Index-0.13

Instability Index27.51

Aliphatic Index 115.56

Aromaticity 0.1111

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1354.06

LogP -10.34

H-bond Donors 49.0

H-bond Acceptors 43.0

Rotatable Bonds 111.0

Heavy Atoms 229.0

Ring Count 4.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0386304 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor antagonist Signaling peptide

TargetPAC1 receptor (Human); PAC1 receptor (Rat); VPAC1 receptor (Human)

Activity30000 nM

MethodIC50