Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC493H803N125O138S7

DescriptionStandard

        MKLFLILIILLFEVPTDAARPRKCFGNIAGYCRKKCEVGEIQEQPCLYKKFCCINEAENKKYQREQELLLSLLQSDQKLDYSVLPTITVLTIQL
    

Molecular Weight10913.86 Da

Isoelectric Point (pI)8.22

Net Charge (pH 7.0)1.45

Net Charge (pH 7.4) 1.12

Charge Density (pH 7.0) 0.0155

GRAVY Index0.01

Hydrophobic Moment 0.56

Boman Index0.03

Instability Index42.89

Aliphatic Index 112.02

Aromaticity 0.0851

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4279.97

LogP -30.20

H-bond Donors 150.0

H-bond Acceptors 147.0

Rotatable Bonds 374.0

Heavy Atoms 763.0

Ring Count 12.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124372 VERIFIED: NO

Provenance & Taxonomy

OrganismMyotis lucifugus [Animal]

FamilyDefensin

Tax ID59463

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence