Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length56 amino acids

Chemical FormulaC272H404N68O72S7

DescriptionStandard

        MGILWFFLIFISLTAHGNAYGPGSCNHEGGLCRVGNCASGEYLAGFCFEPIILCCK
    

Molecular Weight6002.98 Da

Isoelectric Point (pI)5.98

Net Charge (pH 7.0)-1.38

Net Charge (pH 7.4) -1.79

Charge Density (pH 7.0) -0.0246

GRAVY Index0.69

Hydrophobic Moment 0.44

Boman Index0.38

Instability Index19.58

Aliphatic Index 88.93

Aromaticity 0.1429

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2169.86

LogP -16.93

H-bond Donors 80.0

H-bond Acceptors 80.0

Rotatable Bonds 188.0

Heavy Atoms 419.0

Ring Count 13.0

Amide Bonds 58.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0373011 VERIFIED: NO

Provenance & Taxonomy

OrganismTinamus guttatus [Animal]

FamilyBeta-defensin; Defensin

Tax ID94827

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic