Peptide Database

Peptide NameBeta-defensin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length162 amino acids

Chemical FormulaC785H1216N218O241S9

DescriptionStandard

        MRGLLPFLFLLSFFLSPIQAQPEGREEELEETWSEDRDQAPPRVVEESEVVGAENEAGLAAGTYKNRDSPSTGEPPAQSRSPIYFSTAGIPDCGPPSAMRTLYLLLAVLFLVLSQGNAGYGQRSDSYQCHSKRGTCSFSNCPLFRKPYGTCYNGKAKCCLRR
    

Molecular Weight17851.95 Da

Isoelectric Point (pI)5.89

Net Charge (pH 7.0)-1.45

Net Charge (pH 7.4) -1.86

Charge Density (pH 7.0) -0.0090

GRAVY Index-0.42

Hydrophobic Moment 0.47

Boman Index-0.03

Instability Index55.78

Aliphatic Index 66.30

Aromaticity 0.0988

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16305.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7338.11

LogP -81.04

H-bond Donors 259.0

H-bond Acceptors 250.0

Rotatable Bonds 573.0

Heavy Atoms 1253.0

Ring Count 32.0

Amide Bonds 173.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0025617 VERIFIED: NO

Provenance & Taxonomy

OrganismOrnithorhynchus anatinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal