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MYP_143950
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Basic Information
Antibacterial peptide PMAP-23
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
23 amino acids
C140H229N43O28
Standard
Sequence
RIIDLLWRVRRPQKPKFVTVWVR
Physicochemical Analysis
2962.59 Da
12.00
5.76
5.55
0.2504
-0.30
0.76
-0.23
50.85
118.26
0.1304
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1179.68
-4.73
44.0
34.0
95.0
211.0
7.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0295060 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
4 μM
MIC
PMID8132502 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8132502/
RECORD: Rec_0337033 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
9823
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ML35
2 μM
MIC
PMID8132502 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8132502/
RECORD: Rec_0342309 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Cathelicidin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human RBC 50% haemolysis at 29microM
29 μM
Hemolysis
PMID27935673 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27935673/
RECORD: Rec_0348419 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Pseudomonas aeruginosa ATCC 27853
16 μM
MIC
PaperMolecular cloning and chemical synthesis of a novel antibacterial peptide derived from pig myeloid cells.
RECORD: Rec_0361279 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
9823
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
4 μM
MIC
PMID8132502 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8132502/
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