Peptide Database

Peptide NameLactoferrampin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC126H208N36O37

DescriptionStandard

        DGKEDLIWKLLSKAQEKFGKNKSR
    

Molecular Weight2819.22 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1151

GRAVY Index-1.32

Hydrophobic Moment 0.58

Boman Index-0.36

Instability Index32.91

Aliphatic Index 69.17

Aromaticity 0.0833

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1242.27

LogP -11.18

H-bond Donors 43.0

H-bond Acceptors 40.0

Rotatable Bonds 104.0

Heavy Atoms 199.0

Ring Count 3.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232416 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyLactoferrampin

Tax ID9913

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetCandida albicans

MethodMIC

PaperLactoferrampin, an antimicrobial peptide of bovine lactoferrin, exerts its candidacidal activity by a cluster of positively charged residues at the C-terminus in combination with a helix-facilitating N-terminal part | Van Der Kraan, MIA. et al. | DOI: 10.1515/BC.2005.017 Evidence URLhttps://www.uniprot.org/uniprotkb/P24627/entry