Peptide Database

Peptide NameDefensin 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC193H275N53O68S6

DescriptionStandard

        YENPYGCPTDEGKCFDRCNDSEFEGGYCGGSYRATCVCYRT
    

Molecular Weight4617.95 Da

Isoelectric Point (pI)4.44

Net Charge (pH 7.0)-3.29

Net Charge (pH 7.4) -3.60

Charge Density (pH 7.0) -0.0803

GRAVY Index-0.93

Hydrophobic Moment 0.52

Boman Index-0.16

Instability Index12.20

Aliphatic Index 9.51

Aromaticity 0.1707

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1971.04

LogP -25.25

H-bond Donors 75.0

H-bond Acceptors 71.0

Rotatable Bonds 143.0

Heavy Atoms 320.0

Ring Count 9.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0315559 VERIFIED: YES

Provenance & Taxonomy

OrganismAmblyomma hebraeum [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli

Activity30 μM

MethodMIC

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