Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC481H785N127O135S8

DescriptionStandard

        MKLFLVLIILQFEIPTDTARPRKCFSNITGYCRKKCQMGEIYEIACPNGKLCCVNEDLNKKHKKAPESPHSLPQPDEKIDYVILPTTTLLTVRL
    

Molecular Weight10763.67 Da

Isoelectric Point (pI)8.78

Net Charge (pH 7.0)3.62

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.0385

GRAVY Index-0.22

Hydrophobic Moment 0.50

Boman Index-0.02

Instability Index48.42

Aliphatic Index 94.36

Aromaticity 0.0638

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4202.08

LogP -34.05

H-bond Donors 147.0

H-bond Acceptors 149.0

Rotatable Bonds 358.0

Heavy Atoms 751.0

Ring Count 16.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0164145 VERIFIED: NO

Provenance & Taxonomy

OrganismUrsus americanus [Animal]

FamilyDefensin

Tax ID9643

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence