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MYP_143932
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Basic Information
VV-hemorphin-7
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Sensory / Food function ▸ Taste-active peptide
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
9 amino acids
C59H82N14O13
Standard
Sequence
VVYPWTQRF
Physicochemical Analysis
1195.37 Da
8.72
0.73
0.52
0.0814
-0.14
0.46
0.12
-14.06
64.44
0.3333
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
448.57
-1.08
16.0
14.0
32.0
86.0
5.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0076802 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0103849 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]; Bos taurus [Animal]; Mus musculus [Animal]
9823, 9913, 10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Taste Toxin Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
66 μM
IC50
RECORD: Rec_0128268 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Hemorphin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
mu, kappa and delta opioid receptors
PaperGarreau I., Zhao Q., Pejoan C., Cupo A., Piot J. M.. VV-hemorphin-7 and LVV-hemorphin-7 released during in vitro peptic hemoglobin hydrolysis are morphinomimetic peptides. Neuropeptides, 1995, 28, 243-250. PMID7596489 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7596489/
RECORD: Rec_0163149 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
0.066 μM
IC50
PaperPURIFICATION AND CHARACTERIZATION OF ACE INHIBITORY PEPTIDE FROM AQUATIC RESOURCES: A REVIEW
RECORD: Rec_0164950 VERIFIED: NO
Provenance & Taxonomy
Hemoglobin [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
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