MYP_143908
Basic Information
Unnamed
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antifungal
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
not Standard
10 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
WWVXARAXRR
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0056765 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 4,8
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Bacillus megaterium ATCC 14581
0.69 μM
IC50
RECORD: Rec_0061157 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 4,8
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 6538
10 μM
MIC
RECORD: Rec_0066219 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 4,8
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis ATCC 29212
0.65 μM
IC50
RECORD: Rec_0084484 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 4,8
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Bacillus megaterium ATCC 14581
5 μM
MIC
RECORD: Rec_0090783 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Amidation
①The X (position: 4 and 8) in sequence are (S)-2-(4'-pentenyl)-alanine. ②X (4) and X (8) are cross-linked by hydrocarbon stapling through an oct-4-enyl hydrocarbon staple
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
Showing 5 records on this page · Page 2 of 5