Peptide Database

Peptide NameSLAY-screened peptide P4437

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC38H48N6O12S

DescriptionStandard

        YCTYYT
    

Molecular Weight812.89 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.25

Net Charge (pH 7.4) -0.47

Charge Density (pH 7.0) -0.0421

GRAVY Index-0.47

Hydrophobic Moment 0.11

Boman Index0.16

Instability Index69.08

Aliphatic Index 0.00

Aromaticity 0.5000

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 309.97

LogP -1.64

H-bond Donors 13.0

H-bond Acceptors 13.0

Rotatable Bonds 20.0

Heavy Atoms 57.0

Ring Count 3.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0207451 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/