Peptide Database

Peptide NameH8R15

Function Ontology

Anticancer

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC138H238N84O24

DescriptionStandard

        HHHHHHHHRRRRRRRRRRRRRRR
    

Molecular Weight3457.92 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)15.46

Net Charge (pH 7.4) 14.85

Charge Density (pH 7.0) 0.6721

GRAVY Index-4.05

Hydrophobic Moment 0.25

Boman Index-1.79

Instability Index358.23

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1861.46

LogP -23.26

H-bond Donors 77.0

H-bond Acceptors 47.0

Rotatable Bonds 121.0

Heavy Atoms 246.0

Ring Count 8.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0025102 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic Cell-penetrating peptide siRNA delivery

TargetGAPDH siRNA; CHO-K1 and HeLa cells

Methodpeptide/siRNA nanoparticle uptake and gene-silencing assay (qPCR; R/P 2.5–10)