Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length148 amino acids

Chemical FormulaC728H1173N203O206S11

DescriptionStandard

        MLLAIEFFKLVLYFACERSSEVWIANTLHLSLGCSPPLTWNPALPSSRCLPAMRTLALLAAILLVALQAQAEHISVSIDEVVDQQPAQAEDQDVAIYVKEHESSALEALGAKTGGRCVCRKQLLCSYRERRIGDCKIRGVRFPFCCPR
    

Molecular Weight16418.05 Da

Isoelectric Point (pI)7.53

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0047

GRAVY Index0.20

Hydrophobic Moment 0.72

Boman Index0.08

Instability Index52.18

Aliphatic Index 104.86

Aromaticity 0.0676

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6510.77

LogP -57.42

H-bond Donors 235.0

H-bond Acceptors 221.0

Rotatable Bonds 538.0

Heavy Atoms 1148.0

Ring Count 23.0

Amide Bonds 156.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0045506 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal