Peptide Database

Peptide NameDefensin alpha 11

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length104 amino acids

Chemical FormulaC486H800N136O155S10

DescriptionStandard

        MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI
    

Molecular Weight11349.02 Da

Isoelectric Point (pI)6.05

Net Charge (pH 7.0)-1.38

Net Charge (pH 7.4) -1.83

Charge Density (pH 7.0) -0.0133

GRAVY Index-0.12

Hydrophobic Moment 0.61

Boman Index0.03

Instability Index40.80

Aliphatic Index 90.00

Aromaticity 0.0385

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4691.88

LogP -52.79

H-bond Donors 167.0

H-bond Acceptors 166.0

Rotatable Bonds 384.0

Heavy Atoms 787.0

Ring Count 10.0

Amide Bonds 113.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0374988 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence