Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC545H876N148O166S4

DescriptionStandard

        SDLTGHEKFGLGNVKYNISGIHVTAVEFPSASISLLPRSGIKLVIGNASLTIDMNWNIRTWMFKDSGRSTVHISKVFVTAIFSTPLDNMSPASISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12285.94 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)2.72

Net Charge (pH 7.4) 2.32

Charge Density (pH 7.0) 0.0238

GRAVY Index0.07

Hydrophobic Moment 0.55

Boman Index0.12

Instability Index36.98

Aliphatic Index 94.04

Aromaticity 0.0702

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5030.29

LogP -57.42

H-bond Donors 179.0

H-bond Acceptors 176.0

Rotatable Bonds 407.0

Heavy Atoms 863.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0364177 VERIFIED: NO

Provenance & Taxonomy

OrganismPitta sordida [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria