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MYP_143770
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Basic Information
Endothelin-2
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
21 amino acids
C116H165N27O32S4
Standard
Sequence
CSCNSWLDKECVYFCHLDIIW
Physicochemical Analysis
2577.97 Da
4.54
-2.19
-2.51
-0.1043
0.37
0.30
0.22
56.15
88.10
0.1905
12490.00
12740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
947.28
-4.94
37.0
35.0
79.0
179.0
7.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029059 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Endothelin
10116
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-15; 3-11
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Cardiovascular Growth regulation Development regulation Myotropic Receptor modulation Immunomodulatory ACE inhibitory
Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0033018 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-15; 3-11
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0104209 VERIFIED: NO
Provenance & Taxonomy
Atelerix albiventris [Animal]
Endothelin/sarafotoxin
9368
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-15; 3-11
Bio-Activity Profile
Vasoactive Hormone
Evidence URLhttps://www.uniprot.org/uniprotkb/EDN2_ATEAB/entry
RECORD: Rec_0104482 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Endothelin/sarafotoxin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-15; 3-11
Bio-Activity Profile
Vasoactive Hormone
Evidence URLhttps://www.uniprot.org/uniprotkb/EDN2_MOUSE/entry
RECORD: Rec_0124951 VERIFIED: NO
Provenance & Taxonomy
Atelerix albiventris [Animal]
Endothelin
9368
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-15; 3-11
Bio-Activity Profile
Vasoactive Vasoconstrictor
Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
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