Peptide Database

Peptide NameHBD3-GGGGM-HBD2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC417H707N135O113S13

DescriptionStandard

        GIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKKGGGGMGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP
    

Molecular Weight9836.76 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)16.72

Net Charge (pH 7.4) 16.27

Charge Density (pH 7.0) 0.1837

GRAVY Index-0.39

Hydrophobic Moment 0.63

Boman Index-0.14

Instability Index49.12

Aliphatic Index 62.09

Aromaticity 0.0440

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 5220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4008.37

LogP -46.78

H-bond Donors 155.0

H-bond Acceptors 144.0

Rotatable Bonds 333.0

Heavy Atoms 678.0

Ring Count 11.0

Amide Bonds 94.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0422687 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus ATCC 25923

Activity2.5 μM

MethodMIC

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