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MYP_143743
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Basic Information
HBD3-GGGGM-HBD2
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
91 amino acids
C417H707N135O113S13
Standard
Sequence
GIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKKGGGGMGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP
Physicochemical Analysis
9836.76 Da
9.82
16.72
16.27
0.1837
-0.39
0.63
-0.14
49.12
62.09
0.0440
4470.00
5220.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
4008.37
-46.78
155.0
144.0
333.0
678.0
11.0
94.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0003501 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
2.5 μM
MIC
PMID23459290 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23459290/
RECORD: Rec_0217977 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
2.5 μM
MIC
PMID23459290 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23459290/
RECORD: Rec_0339510 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium tuberculosis
2.7
MIC
PMID23459290 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23459290/
RECORD: Rec_0366930 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium tuberculosis H37Rv
6.8
MIC
PMID23459290 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23459290/
RECORD: Rec_0376225 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
0 % hemolysis at 50 μM
Hemolysis
PMID23459290 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23459290/
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