Peptide Database

Peptide NameBacteriocin E50-52 (Preclinical)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Listeria

Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC175H267N51O53S6

DescriptionStandard

        TTKNYGNGVCNSVNWCQCGNVWASCNLATGCAAWLCKLA
    

Molecular Weight4125.69 Da

Isoelectric Point (pI)8.29

Net Charge (pH 7.0)1.34

Net Charge (pH 7.4) 1.05

Charge Density (pH 7.0) 0.0343

GRAVY Index0.16

Hydrophobic Moment 0.45

Boman Index0.18

Instability Index-3.85

Aliphatic Index 65.13

Aromaticity 0.1026

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 18365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1691.54

LogP -21.85

H-bond Donors 64.0

H-bond Acceptors 61.0

Rotatable Bonds 128.0

Heavy Atoms 285.0

Ring Count 7.0

Amide Bonds 45.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0235167 VERIFIED: NO

Provenance & Taxonomy

OrganismEnterococcus faecium [Bacterium]

FamilyBacteriocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Antilisterial Antimycobacterial Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetC.jejuni, Listeria monocytogenes, Listeria spp., Staphylococcus aureus, Salmonella enteritidis, Staphylococcus epidermidis, Y.enterocolitica, Y.pseudotuberculosis

MethodQualitative functional evidence

RECORD: Rec_0246785 VERIFIED: NO

Provenance & Taxonomy

OrganismEnterococcus faecium,Streptococcus faecium [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetCampylobacter jejuni, Yersinia enterocolitica and, Yersinia pseudotuberculosis, Staphylococcus aureus, Staphylococcus epidermidis, Listeria monocytogenes and, Listeria spp

RECORD: Rec_0255779 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterococcus faecium [Bacterium]

FamilyBacteriocin

Tax ID1352

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetListeria ivanovii

RECORD: Rec_0261966 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterococcus faecium [Bacterium]

FamilyBacteriocin

Tax ID1352

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetShigella dysenteriae

RECORD: Rec_0268242 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterococcus faecium [Bacterium]

FamilyBacteriocin

Tax ID1352

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetListeria monocytogenes

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