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MYP_143631
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Basic Information
Bacteriocin E50-52 (Preclinical)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Listeria
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
39 amino acids
C175H267N51O53S6
Standard
Sequence
TTKNYGNGVCNSVNWCQCGNVWASCNLATGCAAWLCKLA
Physicochemical Analysis
4125.69 Da
8.29
1.34
1.05
0.0343
0.16
0.45
0.18
-3.85
65.13
0.1026
17990.00
18365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1691.54
-21.85
64.0
61.0
128.0
285.0
7.0
45.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009727 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecium [Bacterium]
Bacteriocin
1352
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella spp
PMID18293921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18293921/
RECORD: Rec_0010112 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecium [Bacterium]
Bacteriocin
1352
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli O157:H7
1.6 μg/mL
MIC
PMID18293921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18293921/
RECORD: Rec_0010713 VERIFIED: YES
Provenance & Taxonomy
Gram-positive bacteria [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium tuberculosis strain H37Rv
MIC
PMID17347179 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17347179/
RECORD: Rec_0016403 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecium [Bacterium]
Bacteriocin
1352
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
0.2-0.8 μg/mL
MIC
PMID18293921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18293921/
RECORD: Rec_0020525 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecium [Bacterium]
Bacteriocin
1352
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Listeria denitrificans
32 μg/mL
MIC
PMID18293921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18293921/
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