Peptide Database

Peptide NameNisin A

Function Ontology

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Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC153H247N45O46S5

DescriptionStandard

        ITSYSLCTPGCITGRLMGCQFQSAGCNVHVHISK
    

Molecular Weight3613.20 Da

Isoelectric Point (pI)8.54

Net Charge (pH 7.0)1.89

Net Charge (pH 7.4) 1.53

Charge Density (pH 7.0) 0.0557

GRAVY Index0.32

Hydrophobic Moment 0.41

Boman Index0.18

Instability Index38.21

Aliphatic Index 77.35

Aromaticity 0.0588

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1451.22

LogP -18.50

H-bond Donors 55.0

H-bond Acceptors 55.0

Rotatable Bonds 116.0

Heavy Atoms 249.0

Ring Count 5.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0215047 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus salivarius [Bacterium]

FamilyBacteriocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)