Peptide Database

Peptide NameSLAY-screened peptide P1017

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC100H162N30O28S3

DescriptionStandard

        PPCLSYSATRRRYCCLPQIT
    

Molecular Weight2328.74 Da

Isoelectric Point (pI)9.20

Net Charge (pH 7.0)2.93

Net Charge (pH 7.4) 2.82

Charge Density (pH 7.0) 0.1463

GRAVY Index-0.30

Hydrophobic Moment 0.32

Boman Index-0.15

Instability Index107.39

Aliphatic Index 63.50

Aromaticity 0.1000

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 934.82

LogP -10.31

H-bond Donors 38.0

H-bond Acceptors 34.0

Rotatable Bonds 69.0

Heavy Atoms 161.0

Ring Count 5.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0080406 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/