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MYP_143582
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Basic Information
CPF-PG1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
17 amino acids
C79H136N20O21
Standard
Sequence
GFGSLLGKALKIGTNLL
Physicochemical Analysis
1702.05 Da
10.00
1.76
1.55
0.1034
0.81
0.53
0.38
-19.41
143.53
0.0588
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
664.51
-5.27
23.0
23.0
59.0
120.0
1.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006361 VERIFIED: YES
Provenance & Taxonomy
Xenopus pygmaeus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli
25 μM
MIC
PaperHost-defense peptides from skin secretions of the tetraploid frogs Xenopus petersii and Xenopus pygmaeus, and the octoploid frog Xenopus lenduensis (Pipidae).
RECORD: Rec_0049168 VERIFIED: YES
Provenance & Taxonomy
Xenopus pygmaeus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
6 μM
MIC
PaperHost-defense peptides from skin secretions of the tetraploid frogs Xenopus petersii and Xenopus pygmaeus, and the octoploid frog Xenopus lenduensis (Pipidae).
RECORD: Rec_0072309 VERIFIED: YES
Provenance & Taxonomy
Xenopus pygmaeus [Animal]
CPF
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
145.0 μM
HC50
PaperJ.D. King et al. / Peptides 33 (2012) 35-43. Host-defense peptides from skin secretions of the tetraploid frogs Xenopus petersii and Xenopus pygmaeus, and the octoploid frog Xenopus lenduensis (Pipidae)
RECORD: Rec_0088472 VERIFIED: NO
Provenance & Taxonomy
Xenopes pygmaeus [Animal] [Animal]; Xenopus ruwenzoriensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0091145 VERIFIED: YES
Provenance & Taxonomy
Xenopus pygmaeus [Animal]
CPF
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
6.0 μM
MIC
PaperJ.D. King et al. / Peptides 33 (2012) 35-43. Host-defense peptides from skin secretions of the tetraploid frogs Xenopus petersii and Xenopus pygmaeus, and the octoploid frog Xenopus lenduensis (Pipidae)
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