Peptide Database

Peptide NameTemporin-1Sb (Temporin-SHb; Frogs, amphibians, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC76H129N17O19

DescriptionStandard

        FLPIVTNLLSGLLGK
    

Molecular Weight1584.94 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0506

GRAVY Index1.28

Hydrophobic Moment 0.41

Boman Index0.50

Instability Index-4.83

Aliphatic Index 175.33

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 571.50

LogP -2.49

H-bond Donors 19.0

H-bond Acceptors 20.0

Rotatable Bonds 51.0

Heavy Atoms 112.0

Ring Count 2.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0285239 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax saharicus [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetBacillus megaterium

Activity46 μM

MethodMIC

RECORD: Rec_0290178 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax saharicus [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetEnterococcus faecalis ATCC 29212

Activity116 μM

MethodMIC

RECORD: Rec_0347556 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax saharicus [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic

Targethuman erythrocytes

Activity116 μM

MethodLC50

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