Peptide Database

Peptide NameInsulin B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC104H159N27O34S4

DescriptionStandard

        GIVEQCCHKPCTIYELENYCN
    

Molecular Weight2459.80 Da

Isoelectric Point (pI)4.75

Net Charge (pH 7.0)-2.19

Net Charge (pH 7.4) -2.51

Charge Density (pH 7.0) -0.1041

GRAVY Index-0.30

Hydrophobic Moment 0.36

Boman Index0.03

Instability Index38.57

Aliphatic Index 69.52

Aromaticity 0.0952

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 993.09

LogP -9.27

H-bond Donors 36.0

H-bond Acceptors 37.0

Rotatable Bonds 78.0

Heavy Atoms 169.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0171396 VERIFIED: YES

Provenance & Taxonomy

OrganismAtractosteus spatula [Animal]

FamilyInsulin

Tax ID7917

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour