Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC558H884N148O169S4

DescriptionStandard

        PDLSGYEKFGLGNVKYNISRIHVTAVEFPSASISLMPGTGIKLVIENASLTIDMNWNIRTWMFKDNGRSTVYISKVFVTAIFSTPLDNTGHTSISLTSCRTTSGDIDIKLHGKS
    

Molecular Weight12498.14 Da

Isoelectric Point (pI)8.92

Net Charge (pH 7.0)2.22

Net Charge (pH 7.4) 1.97

Charge Density (pH 7.0) 0.0194

GRAVY Index-0.03

Hydrophobic Moment 0.53

Boman Index0.11

Instability Index21.51

Aliphatic Index 89.74

Aromaticity 0.0877

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5082.62

LogP -55.02

H-bond Donors 182.0

H-bond Acceptors 178.0

Rotatable Bonds 412.0

Heavy Atoms 879.0

Ring Count 19.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0145357 VERIFIED: NO

Provenance & Taxonomy

OrganismChordeiles acutipennis (Lesser nighthawk) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria