Peptide Database

Peptide Namel3,4,8,10K5L7

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC72H139N17O13

DescriptionStandard

        KLLLKLKLKLLK
    

Molecular Weight1450.98 Da

Isoelectric Point (pI)10.60

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.3963

GRAVY Index0.59

Hydrophobic Moment 0.39

Boman Index-0.01

Instability Index-47.43

Aliphatic Index 227.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 513.52

LogP 1.70

H-bond Donors 18.0

H-bond Acceptors 18.0

Rotatable Bonds 57.0

Heavy Atoms 102.0

Ring Count 0.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416469 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDiastereomeric peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antibacterial

TargetD-122

Activity>50 μM

MethodLC50

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