Peptide Database

Peptide NameSalivary defensin

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC171H274N58O54S6

DescriptionStandard

        ATCDLASGFGVGSSLCAAHCIARRYRGGYCNSQQVCVCRN
    

Molecular Weight4198.75 Da

Isoelectric Point (pI)8.69

Net Charge (pH 7.0)2.82

Net Charge (pH 7.4) 2.49

Charge Density (pH 7.0) 0.0706

GRAVY Index0.11

Hydrophobic Moment 0.52

Boman Index0.01

Instability Index31.13

Aliphatic Index 63.50

Aromaticity 0.0750

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1825.77

LogP -26.49

H-bond Donors 72.0

H-bond Acceptors 64.0

Rotatable Bonds 135.0

Heavy Atoms 289.0

Ring Count 4.0

Amide Bonds 43.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0119926 VERIFIED: YES

Provenance & Taxonomy

OrganismAnopheles stephensi [Animal]

FamilyDefensin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0175228 VERIFIED: YES

Provenance & Taxonomy

OrganismAnopheles stephensi [Animal]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)