Peptide Database

Peptide NameIPB08(SARS-CoV-2-S (1169-1198)-K)

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC148H257N43O49

DescriptionStandard

        ISGINASVVNIQKEIDRLNEVAKNLNESLIK
    

Molecular Weight3422.88 Da

Isoelectric Point (pI)6.26

Net Charge (pH 7.0)-0.23

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0075

GRAVY Index-0.13

Hydrophobic Moment 0.70

Boman Index-0.01

Instability Index28.37

Aliphatic Index 135.16

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1544.71

LogP -16.71

H-bond Donors 51.0

H-bond Acceptors 49.0

Rotatable Bonds 123.0

Heavy Atoms 240.0

Ring Count 0.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0407529 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermChol

Bio-Activity Profile

Function

Antimicrobial Anti-SARS-CoV-2

TargetSARS-CoV:inhibition of Pseudovirus (PsV) infection in 293T/ACE2 cells(IC=1.13 ± 0.472 μM)

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