Peptide Database

Peptide NameRegenerating islet-derived protein 3-alpha (REG-3-alpha) (Islet of Langerhans regenerating protein 3) (Lithostathine 3) (Pancreatitis-associated protein 2) (Regenerating islet-derived protein III-alpha) (Reg III-alpha) [Cleaved into: Regenerating islet-derived protein 3-alpha 16.5 kDa form; Regenerating islet-derived protein 3-alpha 15 kDa form]

Function Ontology

Antimicrobial

Binding / Molecular interaction ▸ Carbohydrate-binding peptide ▸ Lectin

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length175 amino acids

Chemical FormulaC877H1311N231O254S12

DescriptionStandard

        MLPHLVLNSISWMLLSCLLFVFQVQGEDFQKEVPSPRTSCPMGYKAYRSHCYALVMTPKSWFQADLVCQKRPSGHLVSILSGGEASFVSSLVNGRVDNYQDIWIGLHDPTMGQQPNGGGWEWSNSDVLNYLNWDGDPSSTVNRGHCGSLTASSGFLKWGDYYCDGTLPFVCKFKQ
    

Molecular Weight19538.97 Da

Isoelectric Point (pI)6.16

Net Charge (pH 7.0)-2.12

Net Charge (pH 7.4) -2.73

Charge Density (pH 7.0) -0.0121

GRAVY Index-0.19

Hydrophobic Moment 0.46

Boman Index0.11

Instability Index36.99

Aliphatic Index 73.43

Aromaticity 0.1257

Extinction Coeff. Reduced 48930.00

Extinction Coeff. Oxidized 49305.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7706.71

LogP -77.34

H-bond Donors 271.0

H-bond Acceptors 269.0

Rotatable Bonds 621.0

Heavy Atoms 1374.0

Ring Count 44.0

Amide Bonds 191.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0030288 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Lectin Non-hemolytic

TargetNo Target Organism Found