Peptide Database

Peptide NameInsulin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC103H157N29O32S4

DescriptionStandard

        GIVEQCCHKPCNIFDLQNYCN
    

Molecular Weight2441.78 Da

Isoelectric Point (pI)5.32

Net Charge (pH 7.0)-1.19

Net Charge (pH 7.4) -1.51

Charge Density (pH 7.0) -0.0567

GRAVY Index-0.24

Hydrophobic Moment 0.45

Boman Index0.03

Instability Index68.96

Aliphatic Index 69.52

Aromaticity 0.0952

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1001.51

LogP -10.47

H-bond Donors 35.0

H-bond Acceptors 36.0

Rotatable Bonds 78.0

Heavy Atoms 168.0

Ring Count 4.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0387645 VERIFIED: YES

Provenance & Taxonomy

OrganismOncorhynchus keta [Animal]

FamilyInsulin

Tax ID8018

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0388356 VERIFIED: YES