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MYP_143349
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Basic Information
HALO
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
26 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KKALLXHALHXLALLAXHLAHXLKKA
Physicochemical Analysis
0.00 Da
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0.00
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0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0286952 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
O=Ornithine
Bio-Activity Profile
Antimicrobial Antiparasitic Antiplasmodial
Human erythrocytes
179.2 μM
HC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/18984589/ PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0326685 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,11,17,22
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Trichophyton mentagrophytes
25 μM
MIC
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0374946 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,11,17,22
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Aspergillus fumigatus
50 μM
MIC
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0398406 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,11,17,22
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Enterococcus faecalis
5.6 μM
MIC
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0412955 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
O=ornithine
Bio-Activity Profile
Antimicrobial Antiparasitic Antiplasmodial Histidine-Rich Amphipathic Cationic Peptides
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
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