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MYP_143349
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Basic Information
HALO
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
26 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KKALLXHALHXLALLAXHLAHXLKKA
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0118892 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,11,17,22
Bio-Activity Profile
Hemolytic
human red blood cells
179.2 μM
HC50
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0145430 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,11,17,22
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Candida tropicalis
0.75 μM
MIC
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0150616 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,11,17,22
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Staphylococcus aureus
11.2 μM
MIC
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0182977 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
HALO
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Ornithine (O)
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium falciparum 3D7
11.7 μM
IC50; PLDH assay
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0227046 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,11,17,22
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Staphylococcus aureus ATCC 52156
11.2 μM
MIC
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
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